Professor Dafydd Walters

Head of Section of Child Health in 1994. Having previously been senior lecturer and reader in paediatrics at UCL and became Head of Section of Child Health when the new department of Clinical Developmental Sciences was formed. Research interest is the ion and water transport across the lung epithelium and the way in which this develops in the fetus, the newborn and in later life. This physiological mechanism is essential for normal lung growth, for adaptation to air breathing at birth and for maintenance of normally functioning lungs after birth.

Clinical interests are in general paediatrics with an particular interest in respiratory diseases.

Currently Funded by MRC grant in collaboration with Professor P Kemp (Cardiff) into the role of CNG1 channels in maintenance of pulmonary liquid homeostasis.

Previously secretary of the Association of Clinical Professors of Paediatrics 1998 — 2002.

Chairman of the Physiological Society 2002 — 2004.

RECENT PUBLICATIONS — ORIGINAL RESEARCH PAPERS

Biswas S, Buffery J, Enoch H, Bland M, Markiewicz M and Walters DV (2003) Pulmonary effects of tri-iodothyronine and hydrocortisone supplementation in preterm infants less than 30 weeks gestation: Results of the THORN trial - Thyroid Hormone Replacement in Neonates. Pediatric Research53, 48-56 Biswas S, Buffery J, Enoch H, Bland M, Walters DV and Markiewicz M(2002) A Longitudinal assessment of thyroid hormone concentrations in preterm infants less than 30 weeks gestation during the first two weeks of life and their relationship to outcome. Pediatrics109, 222-227 Junor, RWJ, Benjamin, A, Alexandrou, D, and Walters, DV (2001) The independence of lung liquid absorption in postnatal sheep on pulmonary blood flow, blood gases or perfusion pressure. Experimental Physiology 86.3, 391-398. Junor, RWJ, Benjamin, A, Alexandrou, D, Guggino, S and Walters, DV (2000) Lack of a role for cyclic nucleotide gated cation channels in lung liquid absorption in fetal sheep. Journal of Physiology 523, 493-501 Round, JEC, Junor, RWJ, Gallagher, ME & Walters, DV (1999) The effects of in vivo pulmonary oxygen on lung liquid production in near term fetal sheep. Experimental Physiology 84, 725-738 Junor, RWJ, Benjamin, A, Alexandrou, D, Guggino, S and Walters, DV (1999) A novel role for cyclic nucleotide gated cation channels in lung liquid homeostasis in sheep. Journal of Physiology 520, 255-260

RECENT REVIEWS / BOOK CHAPTERS

Walters, DV  and Olver, RE - Guest Editors (2007) Liquids in the Lung. Respiratory Physiology & Neurobiology Vol: 159 Issue: 3. Wilson,SM, Olver, RE & Walters, DV (2007) Developmental regulation of lumenal lung fluid and electrolyte transport. Respiratory Physiology & Neurobiology 159(3): 247-255. Olver, R E., Walters, D V & Wilson, S M. (2004). Developmental regulation of Lung Liquid Transport. Annual reviews of Physiology 66, 77-101 Walters, D V. (2003) Lung Liquid. (chapter 3) in Neonatal Respiratory Disorders 2cd edition [eds] A Greenough & A Milner. Edward Arnold, London [ISBN 0-340-80813-6] Walters, D V. (2002) Lung lining liquid — the hidden depths. Biology of the Neonate 81, S1, 2-5. The 5th Hans Svenningsen Lecture