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Blood Pressure Unit

The Blood Pressure Unit is a combined clinical and research unit. The major focus of our research includes:

  • Clinical investigations and clinical trials of hypertension
  • Biochemical and molecular biology of hypertension
  • Microcirculation, renovascular and cardiovascular disease

A central theme of the work of the unit revolves around mechanisms controlling sodium excretion, particularly in the renal tubules; identification of molecular abnormalities that may occur in various ion transport mechanisms and whether they may be important in the development of high blood pressure. Current research combines molecular biology, biochemistry and population genetics. A major outcome of the recent work is the recognition of the importance of ethnic origin in biochemical studies of hypertension. This is underscored by the observation of ethnic- dependent differences in the distribution of candidate genes for hypertension and by our recent work on genes coding for the epithelial sodium channel and G-protein subunits

Contact details:

Blood Pressure Unit

St. George's University of London

Cranmer Terrace

London SW17 0RE

( +44 (0)20 8725 3341 / 5413

Fax +44 (0)20 8725 2959

Prof MacGregor is Professor of Cardiovascular Medicine and Honorary Consultant Physician in the Blood Pressure Unit,
Director:

Professor Graham A. MacGregor
MA, FRCP

e-mail Prof. Graham MacGregor

Prof MacGregor is Professor of Cardiovascular Medicine and Honorary Consultant Physician in the Blood Pressure Unit, Department of Medicine at St. George's Hospital Medical School in London, UK.Prof MacGregor received his medical training at Cambridge University in the UK.

He is Chairman of the Blood Pressure Association and recently served as President of the British Hypertension Society, and organiser of CASH, the Consensus Action on Salt and Health.Prof MacGregor's research work has focused on the mechanisms underlying the rise in blood pressure in hypertension, the importance of the renin-angiotensin system, and the influence of salt and potassium intake.His research has also focused on better ways of treating patients, particularly nonpharmacological ways, and also the better use of drugs for the treatment of high blood pressure.Prof MacGregor has authored and co-authored numerous articles for many scientific journals.

Current Research Interests:

Cardiovascular disease

Hypertension

Heart failure

Renal disease

Renin-angiotensin-aldosterone system

Role of dietary sodium and potassium intake in Cardiovascular disease

Sodium transport

 
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