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Then Neurodegeneration Unit is focused on research and teaching
on the pathogenesis of Alzheimer's disease and Prion disease, British and
Danish familial dementias and covering b-Amyloid,
b-Secretase, Oligomer, and fibril desposition,
cholesterol and statin actions. Techniques include proteomics, peptide synthesis,
malditof, protease isolation, electron microscopy, confocal microscopy, antibody
production, cross-linking and apoptosis detection in neuronal cell lines.
Aims are to produce novel therapautic inhibitors. Statins are in clinical
trials.
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